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1.
Pesqui. vet. bras ; 38(5): 896-901, May 2018. tab
Article in Portuguese | LILACS, VETINDEX | ID: biblio-955418

ABSTRACT

O objetivo desse estudo foi investigar a ocorrência de tripanossomose em uma propriedade leiteira no município de Timon no estado do Maranhão, Brasil. O proprietário relatava histórico de abortos, nascimentos de crias fracas e mortalidade de animais adultos com perda progressiva de peso. Foram realizadas visitas à propriedade para obtenção do histórico, exame dos animais e coleta de sangue para realização do teste de Woo, hemogramas, testes sorológicos para pesquisa de anticorpos contra tripanossomose, leptospirose, e neosporose e PCR para diagnóstico molecular de Trypanosoma vivax. A identificação de animais com baixos valores no hematócrito foi a principal alteração hematológica identificada no rebanho. Dois animais foram positivos no teste de Woo, sendo visualizados tripanossomas em esfregaços sanguíneos, confirmados por meio de diagnóstico molecular como sendo T. vivax. Identificou-se que 95,23% (40/42) dos animais com hematócrito baixo foram sorologicamente positivos para T. vivax. As condições identificadas na propriedade, como ambiente propício aos vetores mecânicos, a presença de animais silvestres e a introdução de animais de estados onde já haviam sido registrados surtos de tripanossomose provavelmente estiveram associadas à introdução e disseminação do agente no rebanho. O elevado número de animais sorologicamente positivos para tripanossomose 82,51% (151/183) demonstra que praticamente todo o rebanho teve contato com o agente. O rápido estabelecimento das medidas de controle, entre elas a utilização das drogas tripanocidas, contribuiu para o controle do surto. O estudo permitiu comprovar a ocorrência de mais um surto de tripanossomíase tripanossomose no Brasil. O diagnóstico clínico da enfermidade foi dificultado pela semelhança dos sinais clínicos com outras enfermidades e pela possibilidade da associação de duas ou mais doenças no mesmo paciente, o que ressalta a importância do estabelecimento de medidas diagnósticas adequadas como forma de evitar a disseminação da enfermidade e minimizar as perdas econômicas dos produtores.(AU)


The objective of this study was to investigate the occurrence of trypanosomiasis in a dairy farm in municipality of Timon, State of Maranhão, Brazil. The owner reported abortus, births of weak calves, and mortality of adult animals with progressive weight loss. Visits to the property were carried out to obtain the history, realize animal examination and blood collection for the Woo test, hemograms, serological tests for trypanosomiasis, leptospirosis, and neosporosis and PCR for molecular diagnosis of Trypanosoma vivax. The identification of animals with low values in the hematocrit was the main hematological alteration identified in the herd. Two animals were positive in the Woo test and trypanosomes were visualized in blood smears, confirmed by molecular diagnosis as T. vivax. It was identified that 95.23% (40/42) of the animals with low hematocrit were serologically positive for T. vivax. The conditions identified in the property as an environment propitious to mechanical vectors, the presence of wild animals and the introduction of animals from states where trypanosomiasis outbreaks had already been reported were probably associated with the introduction and dissemination of the agent in the herd. The high number of serologically positive animals for trypanosomiasis 82.51% (151/183) shows that almost all the herd had contact with the agent. The rapid establishment of control measures, including the use of trypanocidal drugs, contributed to the control of the outbreak. The study allowed confirming the occurrence of another outbreak of trypanosomiasis in Brazil. The clinical diagnosis of the disease was difficult by the similarity of the clinical signs of trypanosomiasis with other diseases and the possibility of association of two or more diseases in the same patient, which emphasizes the importance of establishing adequate diagnostic measures as a way to avoid the dissemination of the disease and to minimize the economic losses of the producers.(AU)


Subject(s)
Animals , Cattle , Trypanosomiasis, Bovine/diagnosis , Trypanosomiasis, Bovine/epidemiology , Cattle/parasitology , Trypanosoma vivax/pathogenicity
2.
Mem. Inst. Oswaldo Cruz ; 103(1): 1-13, Feb. 2008. ilus, graf
Article in English | LILACS | ID: lil-478878

ABSTRACT

The biology, epidemiology, pathogenesis, diagnostic techniques, and history of the introduction of Trypanosoma (Duttonella) vivax in the New World are reviewed. The two main immunological responses of trypanosome-infected animals - antibody production and immunodepression - are discussed in the context of how these responses play a role in disease tolerance or susceptibility. Isolation and purification of T. vivax are briefly discussed. The recent reports of bovine trypanosomiasis diagnosed in cattle on farms located in the Pantanal region of the states of Mato Grosso do Sul and Mato Grosso, Brazil, are also discussed.


Subject(s)
Animals , Cattle , Trypanosoma vivax , Trypanosomiasis, Bovine , Africa/epidemiology , Brazil/epidemiology , Genetic Variation , Trypanosoma vivax/classification , Trypanosoma vivax/genetics , Trypanosoma vivax/immunology , Trypanosoma vivax/pathogenicity , Trypanosomiasis, Bovine/diagnosis , Trypanosomiasis, Bovine/epidemiology , Trypanosomiasis, Bovine/parasitology , Trypanosomiasis, Bovine/transmission
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